Read e-book online NK Cells and Other Natural Effector Cells PDF

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By Ronald B. Herberman

ISBN-10: 0123413605

ISBN-13: 9780123413604

ISBN-10: 032313971X

ISBN-13: 9780323139717

NK Cells and different common Effector Cells stories the nation of data on NK cells and different typical effector mechanisms. The insurance of immune effector structures levels from simple reports on their nature, law, and mechanisms of motion to special functional matters corresponding to their position in host resistance, their modulation by means of healing intervention, and adjustments in their job in illness.
The publication is prepared into 12 elements. components I and II research the features of NK cells and different average effector cells, respectively. half III specializes in the telephone lineage of NK and comparable effector cells, delivering proof for or opposed to T cellphone lineage, for or opposed to macrophage lineage, and for or opposed to different or separate lineage. half IV bargains with the genetics of traditional resistance within the mouse and rat. half V provides reports at the law of cytotoxic job. half VI examines the specificity of average effector cells, masking the character of objective telephone constructions and the character of popularity receptors in effector cells. half VII discusses the cytotoxicity by way of cultured lymphoid cells whereas half VIII turns to the mechanisms of cytotoxicity. half IX offers with traditional cell-mediated reactivity opposed to fundamental tumor cells and opposed to non-tumor ambitions. half X examines NK cellphone tumors or the presence of NK cells on the website of tumor progress. half XI provides medical experiences with traditional effector cells. half XII offers proof for in vivo reactivity of common effector cells.

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1975). J. Immunoo. 114:1210. ANALYSIS OF NATURAL KILLER ACTIVITY OF HUMAN LARGE GRANULAR LYMPHOCYTES AT A SINGLE CELL LEVEL Tuomo Timonen^, John R. Ortaldo and Ronald B. , 1981). , 1981). , 1982), surface antigenic phenotype (Ortaldo et al. , 1981), proliferative capacity (Timonen e_t al. , 1981) of NK cells. Although most, if not all, peripheral blood NK activity is exerted by LGL, little information exists as to what proportion of LGL can actually function as NK cells. This question is directly relevant to the reliability of LGL morphology as a marker for NK cells.

H . , j . (1978). Immunol. 120 1415 9 23. , Gartland, G. , Cooper, M. , and Balch, C. 24. VI. 9 Fed. Proc. (In press). Ortaldo, J. , Sharrow, S. , and Herberman, R. ,J. immunol. 127, 2401 (1981). 25. Ault, K. , and Springer, T. ,J. immunol. 1 2 6 , 359 (1981). 26. Lohmann-Matthes, M. , J. Immunol. 123, 1883 (1979). PHENOTYPIC CHARACTERIZATION OF HUMAN NATURAL KILLER AND ANTIBODY-DEPENDENT KILLER CELLS AS AN HOMOGENEOUS AND DISCRETE CELL SUBSET Bice Perussia1 Virginia Fanning Giorgio Trinchieri The Wistar Institute of Anatomy and Biology Philadelphia, Pennsylvania Natural Killer (NK) cells have been identified until now along with "null" lymphocytes (non-B, non-T) characterized by the presence of surface receptors for the Fc fragment of IgG (IgG-FcR) and, on a proportion of them, of receptors for sheep erythrocytes (1).

J. Cancer 21:204 (1978). , and Herberman, R. , J. Nati. Cancer Inst. 49:147 (1972). Reynolds, C. , and Herberman, R. , J. Immunol. 127:282 (1981a). Reynolds, C. , J. Immunol. 127:2204 (1981b). Reynolds, C. , and Herberman, R. , J. Immunol. 126:1581 (1981). , Immunol. Rev. ^4:71 (1979). , et. , Cell Immunol. 4£: 121 (1979a). , Cell Immunol. 48:133 (1979b). , J. Immunol. Methods 36:285 (1980). , Ortaldo, J. , and Herberman, R. , J. Exp. Med. 1S3:569 (1981). , J. Immunol. 124:1683 (1980). 2 Aldo Tagliabue , Diana Boraschi , Sayerio Alberti and Walter Luini 1 2 Sclavo Research Center, Siena, Italy and IRFMN, Milan, Italy.

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NK Cells and Other Natural Effector Cells by Ronald B. Herberman

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